Human LAG-1 (CCL4L1)

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Cat-Nr.100-234
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 90% by SDS-PAGE & HPLC analyses
Length [aa]69
Molecular Weight7.7 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by it's ability to chemoattract CCR5 transfected cells using a concentration of 0.1-10.0 ng/ml
Species ReactivityHuman
SynonymsCCL4L1; LAG1; CCL4L; LAG-1; SCYA4L; AT744.2
DescriptionLAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1beta (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.
Protein SequenceAPMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN
Uniprot IDP13236
Protein RefSeqNP_001001435
mRNA RefSeqNM_001001435

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