Human LAG-1 (CCL4L1)
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| Cat-Nr. | 100-234 |
| Size | 20 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 90% by SDS-PAGE & HPLC analyses |
| Length [aa] | 69 |
| Molecular Weight | 7.7 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by it's ability to chemoattract CCR5 transfected cells using a concentration of 0.1-10.0 ng/ml |
| Species Reactivity | Human |
| Synonyms | CCL4L1; LAG1; CCL4L; LAG-1; SCYA4L; AT744.2 |
| Description | LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1beta (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues. |
| Protein Sequence | APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN |
| Uniprot ID | P13236 |
| Protein RefSeq | NP_001001435 |
| mRNA RefSeq | NM_001001435 |
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