Mouse MEC (CCL28)

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Cat-Nr.M10-090
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]111
Molecular Weight12.6 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract murine lymphocytes using a concentration range of 1.0-10.0 ng/ml.
Species ReactivityHuman, Mouse
SynonymsCcl28; MEC; CCK1; Scya28
DescriptionMEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor and chemoattracts resting CD4, CD8 T-cells and eosinophils. MEC contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MEC is a 12.6 kDa protein containing 111 amino acid residues.
Protein SequenceSEAILPMASS CCTEVSHHVS GRLLERVSSC SIQRADGDCD LAAVILHVKR RRICISPHNR TLKQWMRASE VKKNGRENVC SGKKQPSRKD RKGHTTRKHR TRGTHRHEAS R
Uniprot IDQ9JIL2
Protein RefSeqNP_064675.1
mRNA RefSeqNM_020279

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