Human Epigen

Slide this table

Cat-Nr.100-335S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation98% by SDS-PAGE & HPLC analyses
Length [aa]72
Molecular Weight7.9 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/ml.
Species ReactivityMouse
SynonymsEPGN; EPG; epigen; PRO9904; ALGV3072
DescriptionEpigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant human Epigen is a 7.9 kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.
Protein SequenceAVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA
Uniprot IDQ6UW88
Protein RefSeqNP_001257922.1
mRNA RefSeqNM_001270993.1

All prices plus VAT + possible delivery charges