Human IL-2

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Cat-Nr.200-010
Size50 µg
Price160 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & visualized by silver stain
Length [aa]156
Molecular Weight15.5 kDa
N Terminal SequenceAPTSSSTK and MAPTSSST
Endotoxin Levels< 0.1ng per µg of IL-2
Biological ActivityThe ED50 as determined by the dose-dependent stimulation of proliferation of murine D10G4.1 cells is in the range of 0.1-0.5 ng/ml.
Species ReactivityHuman
Buffer50mM acetic acid
ReconstitutionThe lyophilized IL-2 should be reconstituted in 50mM acetic acid to a concentration not less than 100µg/ml. This solution can be diluted into other buffered solutions or stored at -20 °C for future use.
Stability and StorageThe lyophilized IL-2, though stable at room temperature, is best stored desiccated below 0 °C. Reconstituted IL-2 should be stored in working aliquots at -20 °C. Avoid repeated freeze-thaw cycles.
SynonymsIL2; IL-2; TCGF; lymphokine
DescriptionIL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response.
Protein SequenceMAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLHYKDPAANKARKEAELAAATAEQ
Uniprot IDP60568
Protein RefSeqNP_000577
mRNA RefSeqNM_000586

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