Mouse IL-7

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Cat-Nr.M10-018
Size10 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]130
Molecular Weight15 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityThe ED50 as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
Species ReactivityMouse, Human
ReconstitutionCentrifuge the vial prior to opening!
SynonymsIl7; Il-7; hlb368; A630026I06Rik
DescriptionIL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
Protein SequenceMECHIKDKEG KAYESVLMIS IDELDKMTGT DSNCPNNEPN FFRKHVCDDT KEAAFLNRAA RKLKQFLKMN ISEEFNVHLL TVSQGTQTLV NCTSKEEKNV KEQKKNDACF LKRLLREIKT CWNKILKGSI
Uniprot IDP10168
Protein RefSeqNP_032397.1
mRNA RefSeqNM_008371

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