Human Exodus-2 (CCL21)

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Cat-Nr.100-015
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]111
Molecular Weight12.2 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityDetermined by its ability to chemoattract total lymphocyte population using a concentration range of 10.0-100.0 ng/ml.
Species ReactivityMonkey, Mouse, Human, Leech, Pig
ReconstitutionCentrifuge the vial prior to opening!
SynonymsCCL21; ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21
DescriptionExodus-2 is a CC chemokine that signals through the CCR7 receptor. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant human Exodus-2 is a 12.2 kDa protein containing 111 amino acid residues.
Protein SequenceSDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG P
Uniprot IDO00585
Protein RefSeqNP_002980
mRNA RefSeqNM_002989

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