Human Flt-3 Ligand

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Cat-Nr.100-026-SC
Size50 µg
Price440 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & Coomassie stain
Length [aa]155
Molecular Weight17.6 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 0,5 – 2ng/ml.
Species ReactivityHuman
SynonymsFLT3; FLK2; STK1; CD135; FLK-2
DescriptionFlt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.
Protein SequenceTQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
Uniprot IDP49771
Protein RefSeqNP_001450.2
mRNA RefSeqNM_001459.3

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