Human MCP-4 (CCL13)

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Cat-Nr.100-068S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]75
Molecular Weight8.6 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration of 10.0-100.0 ng/ml.
Species ReactivityMonkey, Mouse, Human, Leech
SynonymsCCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13
DescriptionThe MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-2 is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Protein SequenceQPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
Uniprot IDQ99616
Protein RefSeqNP_005399
mRNA RefSeqNM_005408

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