Mouse KC (CXCL1)

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Cat-Nr.M10-027
Size20 µg
Price199 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]72
Molecular Weight7.8 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml.
Species ReactivityHuman, Rat, Mouse
SynonymsCXCL1
DescriptionAll three isoforms of GRO or KC are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Protein SequenceAPIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK
Uniprot IDP12850
Protein RefSeqNP_032202.1
mRNA RefSeqNM_008176.3

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