Human GRO-beta (CXCL2)
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| Cat-Nr. | 100-032 |
| Size | 10 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 73 |
| Molecular Weight | 7.9 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml. |
| Species Reactivity | Hamster, Human, Mouse |
| Synonyms | CXCL2; GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a |
| Description | Human GROß is a member of the C-X-C family of chemokines and promotes neutrophil and basophil chemotaxis and degranulation. GROß like GROa specifically inhibits growth factor-stimulated proliferation of capillary endothelial cells in a dose-dependent manner. Human GROß is a 7.9 kDa protein containing 73 amino acid residues. |
| Protein Sequence | APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN |
| Uniprot ID | P19875 |
| Protein RefSeq | NP_002080.1 |
| mRNA RefSeq | NM_002089.3 |
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