Human GRO-beta (CXCL2)

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Cat-Nr.100-032
Size10 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]73
Molecular Weight7.9 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.
Species ReactivityHamster, Human, Mouse
SynonymsCXCL2; GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a
DescriptionHuman GROß is a member of the C-X-C family of chemokines and promotes neutrophil and basophil chemotaxis and degranulation. GROß like GROa specifically inhibits growth factor-stimulated proliferation of capillary endothelial cells in a dose-dependent manner. Human GROß is a 7.9 kDa protein containing 73 amino acid residues.
Protein SequenceAPLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN
Uniprot IDP19875
Protein RefSeqNP_002080.1
mRNA RefSeqNM_002089.3

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