Human CTACK/ CCL27

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Cat-Nr.100-145
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]88
Molecular Weight10.2 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract CXCR3 transfected cells using a concentration of 10.0-100 ng/ml.
Species ReactivityMouse, Human, Bacteria
SynonymsCCL27; ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27
DescriptionCTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant human CTACK is a 10.2 kDa protein containing 88 amino acid residues.
Protein SequenceFLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG
Uniprot IDQ9Y4X3
Protein RefSeqNP_006655
mRNA RefSeqNM_006664

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