Human I-TAC (CXCL11) (Animal Free)

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Cat-Nr.100-058-AF
Size20 µg
Price230 €
SourceE. coli
Formulationlyophilized
Purity Confirmation≥ 98% by SDS-PAGE gel and HPLC analyses.
Length [aa]73
Molecular Weight8.3 kDa
Endotoxin Levels< 0.01 ng/ug of protein (< 0.1 EU/ug)
Biological ActivityDetermined by its ability to chemoattract human T-cells activated with IL-2.
Species ReactivityHamster, Mouse, Rabbit, Human, Monkey
SynonymsCXCL11; IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B
DescriptionI-TAC is a 'non-ELR' CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, ormonocytes. Recombinant Human I-TAC (CXCL11) is an 8.3 kDa protein containing 73 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. 
Protein SequenceFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF
Uniprot IDO14625
Protein RefSeqNP_005400.1
mRNA RefSeqNM_005409.4

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