Mouse EGF

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Cat-Nr.M10-003
Size500 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]53
Molecular Weight6.0 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityThe ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Species ReactivityHuman, Mouse, Rat
ReconstitutionCentrifuge the vial prior to opening!
SynonymsEpidermal growth factor; Egf; AI790464
DescriptionEpidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide-bonds.
Protein SequenceNSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR
Uniprot IDP01132
Protein RefSeqNP_036974.1
mRNA RefSeqNM_010113.3

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