Rat IL-4

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Cat-Nr.R20-007S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]126
Molecular Weight14 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityTested by its ability to suppress LPS-induced TNF-α and MIP-2 production in mouse splenocytes.
Species ReactivityMouse, Rat, Human
ReconstitutionCentrifuge the vial prior to opening!
SynonymsIl4; Il4e12
DescriptionInterleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
Protein SequenceMHGCNDSPLR EIINTLNQVT EKGTPCTEMF VPDVLTATRN TTENELICRA SRVLRKFYFP RDVPPCLKNK SGVLGELRKL CRGVSGLNSL RSCTVNESTL TTLKDFLESL KSILRGKYLQ SCTSMS
Uniprot IDP20096
Protein RefSeqNP_958427
mRNA RefSeqNM_201270

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