Human LD78-beta/CCL3L1

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Cat-Nr.100-235
Size20 µg
Price199 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]70
Molecular Weight7.7 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract mouse BaF3 cells expressing the CCR5 receptor using a concentration range of 5-25 ng/ml.
Species ReactivityHuman
SynonymsCCL3L1
DescriptionLD78-beta is a CC chemokine that is closely related to MIP-1 alpha. It signals through the CCR5 receptor and the beta-chemokine receptor, D6. LD78-beta has been shown to exhibit potent activity in HIV suppression assays. Recombinant human LD78-beta is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Protein SequenceAPLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA
Uniprot IDP16619
Protein RefSeqNP_066286.1
mRNA RefSeqNM_021006.4

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