Rat IGF-1

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Size50 µg
Price210 €
SourceE. coli
Purity Confirmation>98.0% as determined by SDS-PAGE
Length [aa]71
Molecular Weight7.6 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityThe ED50 as determined by the stimulation of protein synthesis in rat L6 myoblasts was found to be < 30ng/ml corresponding to a Specific Activity of 33,334IU/mg.
Species ReactivityRat
ReconstitutionIt is recommended to reconstitute the lyophilized rIGF-I in sterile 0.4% NaHCO3 adjusted, not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
SynonymsIgf1; Igf-1; Igf-I; C730016P09Rik
DescriptionIGF-1 is a small protein secreted mainly but not solely by the liver and circulating in blood mostly as a complex with various IGF binding proteins in the blood. It has growth-regulating, insulin-like, and mitogenic activities and it is secreted in response to growth hormone stimulation. Recombinant rat IGF-I produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 71 amino acids and having a molecular mass of 7.6 kDa.
Uniprot IDP08025
Protein RefSeqNP_001075948.1
mRNA RefSeqNM_001082479.1

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