Mouse MIG

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Cat-Nr.M10-034
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]105
Molecular Weight12.2 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoacttract human lymphocytes using a concentration range of 0.1-1.0 ng/ml.
Species ReactivityHuman, Mouse, Monkey, Leech, Rat
SynonymsCxcl9; CMK; Mig; MuMIG; Scyb9; crg-10; BB139920
DescriptionMIG, a CXC chemokine, is produced by IFN stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines
Protein SequenceTLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT
Uniprot IDP18340
Protein RefSeqNP_032625.2
mRNA RefSeqNM_008599.4

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