Mouse SDF-1 alpha (CXCL12)

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Cat-Nr.M10-040
Size10 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]68
Molecular Weight7.9 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human peripheral blood monocytes using a concentration of 50-100 ng/ml.
Species ReactivityHuman, Rat, Mouse, Leech
SynonymsPxorf31
DescriptionSDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant murine SDF-1α is a 7.9 kDa protein containing 68 amino acid residues.
Protein SequenceKPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
Uniprot IDP40224
Protein RefSeqNP_068350.1
mRNA RefSeqNM_021704

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