Mouse C-10 (CCL6)

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Cat-Nr.M10-001
Size10 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]95
Molecular Weight10.7 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityDetermined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 10-100 ng/ml.
Species ReactivityHuman, Bacteria
ReconstitutionCentrifuge the vial prior to opening!
SynonymsGrcc10; PME; ULD; CST6; EPM1; STFB; EPM1A
DescriptionMurine C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues. Recombinant murine C-10 is a 10.7 kDa protein containing 95 amino acid residues.
Protein SequenceGLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA
Uniprot IDO35127
Protein RefSeqNP_038563.1
mRNA RefSeqNM_013535.1

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