Rat IL-15

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Cat-Nr.R20-032S
Size2 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 96% by SDS-PAGE & HPLC analyses
Length [aa]115
Molecular Weight13.5 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityThe ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 105 units/mg.
Species ReactivityHuman, Mouse, Rat
ReconstitutionCentrifuge the vial prior to opening!
SynonymsIl15; 19q11
DescriptionIL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.
Protein SequenceMNWIDVRYDL EKIESLIQFI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VIESGCKECE ELEERNFTEF LQSFIHIVQM FINTS
Uniprot IDP97604
Protein RefSeqNP_037261.1
mRNA RefSeqNM_013129

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