Mouse TFF-2

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Cat-Nr.M10-243S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]106
Molecular Weight11.2 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityNot available!
Species ReactivityMouse
ReconstitutionCentrifuge the vial prior to opening!
SynonymsTrefoil Factor 2, Spasmolytic Polypeptide (SP), Spasmolysin
DescriptionThe Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al.sAm. Journal Respir.Cell Mol. Biol.s(2003) 4: 458-464). Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
Protein SequenceEKPSPCRCSR LTPHNRKNCG FPGITSEQCF DLGCCFDSSV AGVPWCFHPL PNQESEQCVM EVSARKNCGY PGISPEDCAS RNCCFSNLIF EVPWCFFPQS VEDCHY
Uniprot IDQ03404

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