Human IL-16 (130 aa)
Slide this table
| Cat-Nr. | 100-344 |
| Size | 10 µg |
| Price | 190 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 130 |
| Molecular Weight | 13.0 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human CD4+ T lymphocytes using a concentration range of 1.0-100.0 ng/ml. |
| Species Reactivity | Human, Mouse, Leech |
| Synonyms | IL16; LCF; NIL16; PRIL16; prIL-16 |
| Description | IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 13.5 kDa protein consisting of 130 amino acid residues. |
| Protein Sequence | MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS |
| Uniprot ID | Q14005 |
| Protein RefSeq | NP_004504.3 |
| mRNA RefSeq | NM_004513 |
All prices plus VAT + possible delivery charges