Mouse MIP-1 gamma (CCL9/10)
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|> 98% by SDS-PAGE & HPLC analyses
|< 0.1 ng/µg of protein (<1EU/µg)
|Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/ml.
|Ccl9; CCF18; MRP-2; Scya9; Scya10
|MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1γ contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.
|QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
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