Human Apo-SAA1

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Cat-Nr.100-387
Size50 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]105
Molecular Weight~11.7 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
Species ReactivityHuman
SynonymsApo-SAA1
DescriptionRecombinant human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues. Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). The level of Apo-SAA usually is 1-5 μg/ml in plasma. It increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apo-lipoprotein. The human SAA gene codes for a 122 amino acid non-glycosylated polypeptide, which contains an 18 amino acid N-terminal sequence.
Protein SequenceMRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
Uniprot IDP0DJI8
Protein RefSeqNP_000322.2
mRNA RefSeqNM_000331.4

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