Human HCC-1

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Cat-Nr.100-034S
Size2 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 95% by SDS-PAGE & HPLC analyses
Length [aa]72
Molecular Weight8.4 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 5.0-20.0 ng/ml.
Species ReactivityMouse, Human
SynonymsCCL14; CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3
DescriptionHCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues including skeletal muscle, heart, spleen, liver and bone marrow. Recombinant human HCC-1 is an 8.4 kDa protein consisting of 72 amino acids including the four highly conserved residues present in CC chemokines.
Protein SequenceTESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN
Uniprot IDQ16627
Protein RefSeqNP_116739
mRNA RefSeqNM_032963

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