Human HCC-1

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Cat-Nr.100-034S
Size2 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98 by SDS-PAGE & HPLC analyses
Length [aa]66
Molecular Weight7.8 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 5.0-20.0 ng/ml.
Species ReactivityMouse, Human
ReconstitutionCentrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C
Stability and StorageThe lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
SynonymsCCL14; CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3
DescriptionHCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues, including skeletal muscle, heart, spleen, liver, bone marrow and plasma. Mature HCC-1 is found in four different forms, which are distinguished by differential N-terminal truncation and contain 74, 72, 71, or 66 amino acid residues. Recombinant Human HCC-1 (CCL14) is a 7.8 kDa protein consisting of 66 amino acids, including the four highly conserved residues present in CC chemokines.
Protein SequenceGPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
Uniprot IDQ16627
Protein RefSeqNP_116739
mRNA RefSeqNM_032963

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