Human RANTES (CCL 5)

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Cat-Nr.100-095
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]68
Molecular Weight7.8 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityDetermined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.
Species ReactivityCow, Hamster, Monkey, Mouse, Rat, Human, Leech, Bacteria
ReconstitutionCentrifuge the vial prior to opening!
SynonymsCCL5; SISd; SCYA5; RANTES; TCP228; D17S136E
DescriptionRANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Protein SequenceSPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
Uniprot IDP13501
Protein RefSeqNP_002976.2
mRNA RefSeqNM_002985

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