Mouse LIX/CXCL5 (93 aa)

Slide this table

Cat-Nr.M10-114S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]93
Molecular Weight9.8 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityDetermined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml.
Species ReactivityHuman, Mouse
ReconstitutionCentrifuge the vial prior to opening!
SynonymsCxcl5; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II
DescriptionLIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant murine LIX is a 9.8 kDa protein containing 93 amino acid residues.
Protein SequenceAPSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SVQ
Uniprot IDP50228
Protein RefSeqNP_033167.2
mRNA RefSeqNM_009141.2

All prices plus VAT + possible delivery charges