Rabbit Anti-Rat VEGF-A

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Cat-Nr.104-P15
Size100 µg
Price235 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IgG
Species ReactivityRat
Formulationlyophilized from PBS
BufferPBS
ReconstitutionReconstitute in sterile water to a concentration of 0.1-1.0mg/mL.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of rabbits pre-immunized with highly pure (>98%) recombinant Rat VEGF (Rat Vascular Endothelial Growth Factor). Anti-Rat VEGF specific antibody was purified by affinity chromatography employing immobilized Rat VEGF matrix.
AntigenRecombinant Rat VEGF
ApplicationELISA, WB, N
SynonymsVegfa; Vegf; VEGF164
DescriptionRat VEGF (or VEGF-A) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant rat VEGF (isoform 164) is a 38.5 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.
Uniprot IDP16612
Protein RefSeqNP_114024.2.
mRNA RefSeqNM_031836.2

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