Rabbit Anti-Mouse IL-22

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Size100 µg
Price265 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IgG
Species ReactivityMouse
Formulationlyophilized from PBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of goats pre-immunized with highly pure (98%) recombinant murine IL-22. Anti-murine IL-22 specific antibody was purified by affinity chromatography employing immobilized murine IL-22 matrix.
AntigenRecombinant mouse IL-22
ApplicationELISA, WB
SynonymsIL22; IL-22; Iltif; IL-22a; ILTIFa
DescriptionIL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant murine IL-22 is a 3-34 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.
Uniprot IDQ9JJY9
Protein RefSeqNP_058667.1
mRNA RefSeqNM_016971

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