Rabbit Anti-Human MMP-2
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| Cat-Nr. | 102-P112 |
| Size | 100 µg |
| Price | 265 € |
| Category | Polyclonal Antibody |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Preparation | Produced from sera of rabbits immunized with highly pure Recombinant Human MMP-2. Anti-Human MMP-2-specific antibody was purified by affinity chromatography employing an immobilized Human MMP-2 matrix. |
| Antigen | Recombinant Human MMP-2 |
| Application | ELISA, WB |
| Synonyms | MMP2; CLG4; MONA; CLG4A; TBE-1; MMP-II |
| Description | Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant human MMP-2 is a 62.0 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (552 amino acids). |
| Uniprot ID | P08253 |
| Protein RefSeq | NP_004521.1 |
| mRNA RefSeq | NM_004530 |
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