Rabbit Anti-Human MIP-3 alpha

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Size100 µg
Price265 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IgG
Species ReactivityHuman
Formulationlyophilized from PBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human MIP 3 alpha (human Macrophage Inflammatory Protein-3-alpha). Anti-human MIP 3 alpha specific antibody was purified by affinity chromatography employing immobilized human MIP 3 alpha matrix.
AntigenRecombinant human MIP-3 alpha
ApplicationELISA, WB, N
SynonymsCCL20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20
DescriptionMIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3α is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Uniprot IDP78556
Protein RefSeqNP_004582.1
mRNA RefSeqNM_004591

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