Rabbit Anti-Human IFN-beta

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Cat-Nr.102-P26
Size100 µg
Price235 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IgG
Species ReactivityHuman
Formulationlyophilized from PBS
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of rabbits immunized with highly pure recombinant human CCM-2 (Cerebral cavernous malformations 2 protein; aa: Met1-Ala444; SwissProt: #Q9BSQ5) as the immunizing antigen. Anti-human CCM-2 was purified by affinity chromatography with immobilized Protein A.
AntigenRecombinant human IFN-beta
ApplicationELISA, WB, N
SynonymsIFNB1; IFB; IFF; IFNB;
DescriptionInterleukin 6 (IL-6), also known as interferon-beta 2, 26 kDa protein and B cell stimulatory factor-2 (BSF-2), is a pleiotropic α-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism, and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22 kDa - 28 kDa phosphorylated and variably glycosylated molecule. Mature human IL-6 is 183 amino acids (aa) in length and shares 41% aa sequence identity with mouse and rat IL-6. Alternate splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties.
Uniprot IDP01574
Protein RefSeqNP_002167.1
mRNA RefSeqNM_002176

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