Rabbit Anti-Rat VEGF-D

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Cat-Nr.104-PA12
Size200 µg
Price225 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IG
Species ReactivityRat
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
PreparationProduced from sera of rabbits immunized with an N-terminal peptide of rat dNdC-VEGF-D. Anti-rat VEGF-D IgG was purified by affinity chromatography with immobilized Protein A.
AntigenN-terminal peptide
ApplicationWB, E
Synonymsvascular endothelial growth factor D; Figf
DescriptionVascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), is a vascular endothelial growth factor. This secreted protein is a member of the platelet derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and performs activities in angiogenesis, lymphangiogenesis, and endothelial cell growth. Human VEGF-D is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. It is structurally and functionally similar to VEGF-C, and is secreted as a non-covelent homodimer in a antiparallel fashion. VEGF-D undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. Like VEGFC, it may particularly be involed in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults.
Uniprot IDO35251
Protein RefSeqNP_113949.1
mRNA RefSeqNM_0371761.1

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