Rabbit Anti-Mouse VEGFR-2/Flk-1 (Peptide), soluble

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Cat-Nr.103-PA19S
Size100 µg
Price175 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IG
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
PreparationProduced from sera of rabbits immunised with a peptide of the C-terminal end of native mouse soluble VEGFR-2/Flk-1 (GMEASLGDRIAMP). Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A.
Antigenpeptide: GMEASLGDRIAMP
ApplicationWB
Synonymssoluble vascular endothelial growth factor receptor-2 ; soluble Kdr; soluble Ly73; soluble Flk-1; sVEGFR2; sVEGF receptor 2; soluble kinase insert domain protein receptor
DescriptionThe antibody recognizes solely the endogenous soluble form of mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. The endogenous soluble mouse esFlk-1 generated by alternative splicing consists of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle; other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C; ligand binding plays a key role in vascular development and vascular permeability.
Uniprot IDP35918
Protein RefSeqACJ66293.1
mRNA RefSeqEU884114

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