Rabbit Anti-Human Galectin-3
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| Cat-Nr. | 102-P228 |
| Size | 100 µg |
| Price | 265 € |
| Category | Polyclonal Antibody |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant Galectin-3. Anti-Human Galectin-3 specific antibody was purified by affinity chromatography employing immobilized Galectin-3 matrix. |
| Antigen | Recombinant human Galectin-3 |
| Application | ELISA, WB |
| Synonyms | LGALS3; L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2 |
| Description | The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities. |
| Uniprot ID | P17933 |
| Protein RefSeq | NP_002297.4 |
| mRNA RefSeq | NM_002308 |
Reference
- Pectasol‐C Modified Citrus Pectin targets Galectin‐3‐induced STAT3 activation and synergize paclitaxel cytotoxic effect on ovarian cancer spheroids. Hossein G. et al., Cancer Med. 2019 Aug; 8(9): 4315–4329.
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