Rabbit Anti-Human CXCR4
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| Cat-Nr. | 102-PA120AG |
| Size | 50 µg |
| Price | 230 € |
| Category | Polyclonal Antibody |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots. |
| Preparation | Purified from sera of rabbits immunized with highly pure recombinant human CXCR4 fusion protein [N-terminal and extracellular loops] Purified in E. coli. |
| Antigen | Recombinant human CXCR4 fusion protein [N-terminal and loops] |
| Application | WB, E |
| Synonyms | CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E |
| Description | Chemokine receptors are seven-transmembrane domain G-protein coupled receptors that mediate the biological activities of chemokines. Most of these receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. They are named according to the chemokine subfamily they bind. There are currently six CXC-specific receptors designated CXCR1 to CXCR6. |
| Uniprot ID | P61073 |
| Protein RefSeq | NP_001008540.1 |
| mRNA RefSeq | NM_001008540.1 |
Figures
Western Blot analysis with recombinant human CXCR4 fusion protein produced in E. coli.
Immunofluorescence staining (green) of cryo-sections of human lung tissue and forskin (fixed 15 min in 4% PFA) with anti-human CXCR4 (5µg/ml) [Cat# 103-PA120AG] and counter staining of nuclei with Dapi.
Specimen provided by Prof. Dr. J. Wilting, Goettingen.
The experiment was performed by the research group of Prof. Dr. J. Wilting, University Göttingen, Germany.
Immunofluorescence staining (green) of cryo-sections of human foreskin (fixed 15 min in 4% PFA) with anti-human CXCR4 (5µg/ml) [Cat# 103-PA120AG] and counter staining of nuclei with Dapi (left). Right: Negative control.
Note staining in epidermis and scattered cells in the dermis.
The experiment was performed by the research group of Prof. Dr. J. Wilting, University Göttingen, Germany.
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