Rabbit Anti-Human CEACAM-1 (D1-4)
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Cat-Nr. | 102-PA100S |
Size | 100 µg |
Price | 185 € |
Category | Polyclonal Antibody |
Clone Nr. | Rabbit IgG |
Species Reactivity | Human |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots. |
Preparation | Produced from sera of rabbits immunized with highly pure recombinant human soluble CEACAM-1 (D1-4) (Carcinoembryonic antigen-related cell adhesion molecule-1; SwissProt: #P13688) as the immunizing antigen. Anti-human soluble CEACAM-1 was purified by affinity chromatography with immobilized Protein A. |
Antigen | Recombinant human sCEA-1 (D1-4) |
Application | E, WB, FC |
Synonyms | CEACAM1; BGP; BGP1; BGPI, CD66a |
Description | Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist. |
Uniprot ID | P13688 |
Protein RefSeq | NP_001192273.1 |
mRNA RefSeq | NM_001205344 |
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