Rabbit Anti-Human CEACAM-1 (D1-4)
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| Cat-Nr. | 102-PA100S |
| Size | 100 µg |
| Price | 175 € |
| Category | Polyclonal Antibody |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots. |
| Preparation | Produced from sera of rabbits immunized with highly pure recombinant human soluble CEACAM-1 (D1-4) (Carcinoembryonic antigen-related cell adhesion molecule-1; SwissProt: #P13688) as the immunizing antigen. Anti-human soluble CEACAM-1 was purified by affinity chromatography with immobilized Protein A. |
| Antigen | Recombinant human sCEA-1 (D1-4) |
| Application | E, WB, FC |
| Synonyms | CEACAM1; BGP; BGP1; BGPI, CD66a |
| Description | Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist. |
| Uniprot ID | P13688 |
| Protein RefSeq | NP_001192273.1 |
| mRNA RefSeq | NM_001205344 |
Figures
Western Analysis with anti-human CEACAM1.
Both antibodies recognize CEACAM1 but not CEACAM8. Cross reaction with CEACAM3, CEACAM4, CEACAM5, CEACAM6 und CEACAM7 are not tested so far.
The experiments were performed by PD Dr. Bernhard Singer, Institute of Anatomy, Medical Faculty, University Duisburg-Essen, Germany.
Immunohistochemistry (IHC) staining of CEACAM1 in human prostate tissue using the polyclonal rabbit anti-human CEACAM1 antibody [Cat# 102-PA100, #D1-4] with DAB staining.
The experiments were performed by PD Dr. Bernhard Singer, Institute of Anatomy, Medical Faculty, University Duisburg-Essen, Germany.
Immunohistochemistry (IHC) staining of CEACAM1 in human prostate tissue using the polyclonal rabbit anti-human CEACAM1 antibody [Cat# 102-PA100, #D1-4] with DAB staining.
The experiments were performed by PD Dr. Bernhard Singer, Institute of Anatomy, Medical Faculty, University Duisburg-Essen, Germany.
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