Rabbit Anti-Human CEACAM-1 (D1-4)

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Cat-Nr.102-PA100S
Size100 µg
Price185 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IgG
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
PreparationProduced from sera of rabbits immunized with highly pure recombinant human soluble CEACAM-1 (D1-4) (Carcinoembryonic antigen-related cell adhesion molecule-1; SwissProt: #P13688) as the immunizing antigen. Anti-human soluble CEACAM-1 was purified by affinity chromatography with immobilized Protein A.
AntigenRecombinant human sCEA-1 (D1-4)
ApplicationE, WB, FC
SynonymsCEACAM1; BGP; BGP1; BGPI, CD66a
DescriptionCarcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.
Uniprot IDP13688
Protein RefSeqNP_001192273.1
mRNA RefSeqNM_001205344

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