Rabbit Anti-Rat IL-10

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Size100 µg
Price265 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IgG
Species ReactivityRat
Formulationlyophilized from PBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of rabbits pre-immunized with highly pure (>98%) recombinant rat IL-10. Anti-rat IL-10 specific antibody was purified by affinity chromatography employing immobilized rat IL-10 matrix.
AntigenRecombinant rat IL-10
ApplicationELISA, WB
SynonymsIl10; IL10X
DescriptionInterleukin 10 (IL-10), initially designated cytokine synthesis inhibitory factor (CSIF), was originally identified as a product of mouse T helper (Th) 2 clones that inhibited cytokine production by Th1 clones . The human ortholog of mouse IL-10 was subsequently cloned by cross-hybridization. Human and mouse IL-10 are 81% identical at the nucleotide and amino acid level. IL-10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. A number of viruses, including Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV), also encode viral members of the IL-10 family. Human IL-10 has cross-species actvity and is active on mouse cells. Mouse and rat IL-10 is species-specific and does not act on human cells.
Uniprot IDP29456
Protein RefSeqNP_036986
mRNA RefSeqNM_012854

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