Rabbit Anti-Human FGF-7/KGF
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|Clone Nr.||Rabbit IgG|
|Formulation||lyophilized from PBS|
|Reconstitution||Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.|
|Stability and Storage||The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.|
|Preparation||Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human KGF (hKGF). Anti-human FGF-7 (KGF) specific antibody was purified by affinity chromatography employing immobilized human KGF matrix.|
|Antigen||Recombinant human KGF (FGF-7)|
|Application||ELISA, WB, N|
|Description||Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Human KGF/FGF-7 is an app. 19 kDa protein consisting of 163 amino acid residues.|
- A Bioengineering Approach for the Development of Fibroblast Growth Factor-7-Functionalized Sericin Biomaterial Applicable for the Cultivation of Keratinocytes. A. A. Lian et al., Int J Mol Sci. 2022 Sep; 23(17): 9953.
- Effects of transgenic silk materials that incorporate FGF‐7 protein microcrystals on the proliferation and differentiation of human keratinocytes. R. Maruta et al., FASEB Bioadv. 2020 Dec; 2(12): 734–744.
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