Goat Anti-Rat IFN-gamma

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Cat-Nr.104-P03G
Size100 µg
Price235 €
CategoryPolyclonal Antibody
Clone Nr.Goat IgG
Species ReactivityRat
Formulationlyophilized from PBS
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of rabbits pre-immunized with highly pure recombinant Rat IFN-gamma. Anti-Rat IFN-gamma specific antibody was purified by affinity chromatography employing immobilized Rat IFN-gamma matrix.
AntigenRecombinant rat IFN-gamma
ApplicationELISA, WB, IHC (P)
SynonymsIfng; IFNG2;
DescriptionIFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant rat IFN-γ is a 15.6 kDa protein containing 135 amino acid residues.
Uniprot IDP01581
Protein RefSeqNP_620235.1
mRNA RefSeqNM_138880.2

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