Rabbit Anti-Mouse VEGF-A

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Cat-Nr.103-PABi03
Size50 µg
Price230 €
CategoryPolyclonal Antibody
LabelBiotin
Clone Nr.Rabbit IgG
Species ReactivityMouse, Human
Formulationlyophilized
BufferPBS
Stabilizer/CarrierBSA (50x), 0.02% sodium azide
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
PreparationProduced from sera of rabbits immunized with highly pure recombinant murine VEGF164. Anti-murine VEGF-A was purified by affinity chromatography with immobilized Protein A.
AntigenRecombinant mouse VEGF164 (RT #M30-001)
ApplicationE
SynonymsVegfa; Vpf; Vegf; Vegf120; Vegf164; Vegf188
DescriptionMouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF (isoform 164) is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.
Uniprot IDQ00731
Protein RefSeqNP_001020421
mRNA RefSeqNM_001025250

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