Rabbit Anti-Mouse VEGFR-2/Flk-1

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Cat-Nr.103-PA18S
Size100 µg
Price175 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IG
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
AntigenRecombinant mouse esFlk-1 (RT Cat# S01-M04)
ApplicationWB
Synonymssoluble vascular endothelial growth factor receptor-2 ; sKdr; sLy73; sFlk-1; sVEGFR2; sVEGF receptor 2; skinase insert domain protein receptor
DescriptionThe antibody recognizes mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle; other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C; ligand binding plays a key role in vascular development and vascular permeability.
Uniprot IDP35918
Protein RefSeqACJ66293.1
mRNA RefSeqEU884114

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