Goat Anti-Mouse MCP-3

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Size100 µg
Price265 €
CategoryPolyclonal Antibody
Clone Nr.Goat IgG
Species ReactivityMouse
Formulationlyophilized from PBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of rabbits pre-immunized with highly pure (>98%) recombinant murine MCP-3 (murine Macrophage/Monocyte chemotactic protein-3). Anti-murine MCP-3 specific antibody was purified by affinity chromatography employing immobilized murine MCP-3 matrix.
AntigenRecombinant Mouse MCP-3
ApplicationELISA, WB
SynonymsCcl7; fic; marc; mcp3; MCP-3; Scya7
DescriptionSequence comparisons suggest that MARC may be the mouse homologue of the human MCP 3 gene. Mouse MARC/MCP3 expression has also been detected during murine experimental allergic encephalomyelitis in the spinal cord, and in LPS-stimulated murine WEHI 3 cells and Swiss 3T3 cells where MARC expression is glucocorticoidattenuated. Except for one amino acid subsititution, mouse MARC is identical to mouse FIC, the product of a growth factoractivated gene. The mouse MARC cDNA encodes a 97 amino acid residue precursor protein with a 23 amino acid residue signal peptide that is cleaved to yield a 74 amino acid residue mature protein. Mouse CCR2, a mouse chemokine receptor, has been shown to bind JE/MCP1 with high affinity and MARC/MCP3 with lower affinity.
Uniprot IDQ03366
Protein RefSeqNP_038682.1
mRNA RefSeqNM_013654.3

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