Human FGFR-3(IIIb)S249C/Fc Chimera, soluble
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| Cat-Nr. | SFC-026 |
| Size | 20 µg |
| Price | 370 € |
| Source | Insect cells |
| Label | Fc-Tag |
| Formulation | lyophilized |
| Length [aa] | 585 |
| Molecular Weight | 65.0kDa |
| N Terminal Sequence | ESLGT |
| Species Reactivity | Human |
| Synonyms | Fibroblast growth factor receptor 3, FGFR-3/ CD333 |
| Protein Sequence | ESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERCPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKSWISESVEADVRLRLANVSERDGGEYLCRATNFIGVAEKAFWLSVHGPRAAEEELVEADEAGSVYAGTRSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Uniprot ID | P22607-2 |
| Protein RefSeq | NP_001156685.1 |
| mRNA RefSeq | NM_001163213.1 |
Figures
SDS-PAGE analysis recombinant human soluble FGFR-3(IIIb)S249C/Fc produced in insect cells. Sample was loaded in 12.5% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue.
Functional ELISA: Recombinant human aFGF and FGF2 were coated with 1µg/ml in PBS and recombinant human sFGFR3(IIIc/Fc), sFGFR3(IIIb)/Fc, sFGFR3(IIIb)S249C/Fc and sFGFR3(IIIa)/Fc were added to the well (1µg/ml). Detection was performed using a mouse anti-human FGFR3 antibody (Santa Cruz #sc-13121) and a conjugated goat anti-mouse polyclonal antibody for detection.
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