Human BAFF receptor, soluble
Slide this table
Cat-Nr. | S01-038S |
Size | 10 µg |
Price | 95 € |
Source | E. coli |
Formulation | lyophilized |
Purity Confirmation | > 95% by SDS-PAGE & HPLC analyses |
Length [aa] | 76 |
Molecular Weight | 7.7 kDa |
Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
Biological Activity | Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0-4.0 μg/ml in the presence of 1.0 μg/ml of human soluble BAFF. |
Species Reactivity | Mouse |
Synonyms | TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin |
Description | BAFF Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFF-R/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFF-R is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extracellular portion of the full BAFF-R protein. |
Protein Sequence | MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG |
Uniprot ID | Q96RJ3 |
Protein RefSeq | NP_443177 |
mRNA RefSeq | NM_052945 |
All prices plus VAT + possible delivery charges