Description / human FGF-10 protein
Fibroblast Growth Factor-10 (FGF-10) is a heparin binding growth factor which stimulates the proliferation and activation of cells that express FGF receptors. FGF-10 is most related to KGF/FGF-7 and is expressed during development and preferentially in adult lungs. Human FGF-10 is a 19.3 kDa protein containing 170 amino acid residues.
More Information
| Size | 5 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. |
| N Terminal Sequence | MLGQDM |
| Purity Confirmation | > 95% by SDS-PAGE |
| Length [aa] | 170 |
| Molecular Weight | 19.3 kDa |
| Species Reactivity | Chicken, Mouse, Human |
| Formulation | lyophilized |
| Buffer | 0.5xPBS |
| Protein Sequence | MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS |
| Reconstitution | The lyophilized FGF-10 should be reconstituted in water to a concentration not lower than 50 μg/ml. For long term storage we would recommend to add at least 0.1% human or bovine serum albumin. |
| Stability and Storage | Lyophilized samples are stable for more than six months at -20°C to -70°C. |
| Synonyms | FGF10; KGF2 |
| Uniprot ID | O15520 |
| Protein RefSeq | NP_004456.1 |
| mRNA RefSeq | NM_004465 |
| Adult stem cells-derived organoids | Endometrium, Fallopian tube, Gallbladder, Kidney tubule, Liver, Lung, Mammary, Oesophagus, Oral mucosa, Pancreatic duct, Stomach, Urothelium |
| Pluripotent stem cells-derived organoids | Esophagus, Lung, Mammary |