Description / FGF-10
Fibroblast Growth Factor-10 (FGF-10) is a heparin binding growth factor which stimulates the proliferation and activation of cells that express FGF receptors. FGF-10 is most related to KGF/FGF-7 and is expressed during development and preferentially in adult lungs. Human FGF-10 is a 19.3 kDa protein containing 170 amino acid residues.
More Information
Size | 25 µg |
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Source | E. coli |
Biological Activity | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. |
N Terminal Sequence | MLGQDM |
Purity Confirmation | > 95% by SDS-PAGE |
Length [aa] | 170 |
Molecular Weight | 19.3 kDa |
Species Reactivity | Chicken, Mouse, Human |
Formulation | lyophilized |
Buffer | 0.5xPBS |
Protein Sequence | MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS |
Reconstitution | The lyophilized FGF-10 should be reconstituted in water to a concentration not lower than 50 μg/ml. For long term storage we would recommend to add at least 0.1% human or bovine serum albumin. |
Stability and Storage | Lyophilized samples are stable for more than six months at -20°C to -70°C. |
Synonyms | FGF10; KGF2 |
Uniprot ID | O15520 |
Protein RefSeq | NP_004456.1 |
mRNA RefSeq | NM_004465 |
Adult stem cells-derived organoids | Endometrium, Fallopian tube, Gallbladder, Kidney tubule, Liver, Lung, Mammary, Oesophagus, Oral mucosa, Pancreatic duct, Stomach, Urothelium |
Pluripotent stem cells-derived organoids | Esophagus, Lung, Mammary |