Description / anti-human FGF-10 monoclonal antibody
FGF-10 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to KGF/FGF-7 and is expressed during the development and preferentially in adult lungs. It signals through the FGFR 2b.
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| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#6L27) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of fibroblast growth factor receptor 10 (also called keratinocyte growth factor-2 (KGF-2)). |
| Antigen | Recombinant human FGF-10 |
| Application | WB |
| Synonyms | FGF10; KGF2 |
| Uniprot ID | O15520 |
| Protein RefSeq | NP_004456.1 |
| mRNA RefSeq | NM_004465 |