anti-human VEGFR-2/KDR (Peptide), soluble polyclonal antibody Biotin-conjugated Anti-Human 50 µg

Cat-Nr.
102-PABi19
Size
50 µg
€193.00

Description / anti-human VEGFR-2/KDR (Peptide), soluble polyclonal antibody Biotin-conjugated

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

More Information

Size 50 µg
Source Rabbit
Biological Activity Western Blot: Use 1-5 µg/ml
Clone Nr. Rabbit IgG
Species Reactivity Human
Formulation lyophilized
Buffer PBS + 50x BSA + 0.012 % Sodium Azide
Reconstitution Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and Storage The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50%
Preparation Produced from sera of rabbits immunised with a peptide of the C-terminal end of native human soluble VEGFR-2/KDR (CGRETILDHSAEAVGMP). Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A.
Antigen Peptide: CGRETILDHSAEAVGMP.
Application WB
Synonyms soluble vascular endothelial growth factor receptor-2 ; soluble KDR; soluble FLK1; soluble CD309; VEGF receptor 2; sKDR
Uniprot ID P35968
Protein RefSeq NP_002244.1
mRNA RefSeq NM_002253.2

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