Description / anti-bovine SRY polyclonal antibody
The „Sex determining region of Y-Gen” (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex.
More Information
| Size | 100 µg |
|---|---|
| Source | Rabbit |
| Biological Activity | Western Blot: Use 1-5 µg/ml |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Bovine |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% |
| Antigen | Recombinant bovine SRY (RT #B30-001) |
| Application | WB |
| Synonyms | Sex-determining region Y protein; Testis-determining factor |
| Uniprot ID | Q03255 |
| Protein RefSeq | NP_001014407.1 |
| mRNA RefSeq | NM_001014385.1 |